My husband told me with glee that Nicholas Byfield had a great big stone ‘like flint’ in his bladder, weighing 33 ounces, which ‘exceedingly afflicted’ him for 15 years, until it killed him in 1622, aged 44. It did not stop him writing about the Epistle to the Colossians and remarking that Christ’s divine nature is ‘incircumscriptible in respect of place’.