Sir Jeremy Farrar, the head of the Wellcome Trust, writes that ‘the last year has been an eye-opener for me. I thought, probably like most people, that the world works through official or formal channels, but much of it operates through private phone calls or messaging apps’. Hence his book, written with the journalist Anjana Ahuja, is a gossipy, sometimes angry, fast-paced tale, which quotes frequently from his own messages sent to other important people.